In order to protect themselves against enemies, players can hide behind structures like walls. Each class is equipped with different weapons. There are three classes available for players to choose from namely assault, short range, and tactical. In order to travel between maps in an effective way, the game features repurposed climbing gear, as well as 'Terrain Spikes', which can be used for traversing tough ground. The game features gadgets like semi-automatic rifles, shotguns, pistols, grenades and explosives, as well as unusual melee-weapons like Brainer combat axes. The game's maps are described as 'compact battle zones' which have traditional historic Resident Evil themes and environments. Players can choose to play from a first-person perspective, or a third-person perspective. Players play as a mercenary from two different corporations, and they are tasked to co-operate with their fellow mercenaries to eliminate all the hostile players. Umbrella Corps is a competitive multiplayer shooter that features zombies.

As a result, these global corporations send mercenaries into several zombie infested sites to search for Umbrella's lost secrets. Several corporations feverishly desire possession of Umbrella's assorted remnants and secrets – most especially those involving their bio-weapons technologies, a search that inevitably brings them into direct conflict with other corporations which are also seeking the same things. Settings that resemble locations that have been destroyed such as the Spencer Mansion and Raccoon City are explained as being recreations for training purposes. The game lists 10 competing organizations using their own special forces to retrieve the old Umbrella Corporation's lost research: Suntech Samurai Co., Suntech Ninja Co., Medvedev, Sheng-Ya Pharmaceutical, Aeolus Edge East, Aeolus Edge West, Tenenti Inc., Saurian Corporation, Akembe Chemical, and Rashid-Sahir Industries. Although the Umbrella Corporation has been disbanded, a great deal of valuable viral Bio-organic Weapons (BOW) research information left over from their past evil endeavours is still waiting to be discovered. The multiplayer portion takes place in 2016, three years after the events of Resident Evil 6 and 13 years after the collapse of the Umbrella Corporation in 2003/2004. The Experiment ends with 3A-7 overcoming all odds and surviving all of the missions, scaring his superiors. Once the testing is successful, his superiors try to kill him by sending him on more dangerous missions. He is sent on missions by superiors in order to test out new equipment such as the Zombie Jammer. The organization he belongs to, the Umbrella Co., is revealed to have the full name of the 'Umbrella Corporation' in Resident Evil 7: Biohazard a new organization using Umbrella's name. The single-player portion, 'The Experiment', takes place in 20.

Wesker umbrella corps